I confirm this issue. Radzen 2.43.0 for Windows will fail to download the 2.43.1 update because of this issue: https://github.com/electron/electron/issues/21566
Long story short if you have Radzen 2.43.0 it will fail to start now that we shipped 2.43.1 
The solution is to manually download latest Radzen from our web site.
P.S. Upgrading Electron was never a pleasant experience. This time it is far worse though. Hope the security updates and performance improvements are worth it.