appreciate any direction on how to interrogate a file uploaded by RadzenUpload component
I am not quite sure what "interrogate a file" means. A file is uploaded via the UploadController and you can modify the code there to do whatever you want with the file.
I mean read the contents of the file
Reading the contents of the uploaded file isn't specific to Radzen. You can use the general .NET approach described here c# - How to read contents of uploaded files in asp.net mvc - Stack Overflow
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