Will you be implementing support for the new Microsoft.Data.SqlClient going forward (I know it still in preview atm)? We have databases with encrypted columns and this would provide support for that scenario.
Radzen relies on Entity Framework Core for database access. If Microsoft supports that version of Microsoft.Data.SqlClient it will be available in Radzen too. For the time being it seems that they don't. A possible workaround is to use Microsoft.Data.SqlClient from custom code as shown here. That example still uses EF but that can probably be replaced with using SqlDataReader.