In iis7 new features will filter out folder name where contains dot, therefore, "_content/Radzen.Blazor/Radzen.Blazor.js" static file will return 404 not found, hope see another solution, thanks!
By the way, In iis6 everything runs fine.
RCL's static web assets only work on "ASPNETCORE_ENVIRONMENT" environment variable was set with "Development", and I tried to set "Release", vs local run has same error condition.
The following is what I have referred to resolve, local was work, but on iis7 it not work.