Does radzen number only validator exist? or phone number?

Check the implementations that I linked above. You can create a custom validator and set all existing emails as a property and then check against if that property contains the component value. Something like:

namespace MyApp
{
    public class UniqueEmailValidator : Radzen.Blazor.ValidatorBase
    {
        [Parameter]
        public override string Text { get; set; } = "Email exists";

        protected override bool Validate(IRadzenFormComponent component)
        {
            var email = component.GetValue();

            return email != null && Emails != null && !Emails.Contains(email.ToString());
        }

        [Parameter]
        public IEnumerable<string> Emails { get; set; }
    }
}
<RadzenTextBox @bind-Value=@email Name="EmailTextBox" />
<UniqueEmailValidator Component="EmailTextBox" Emails=@emails />

@code {
     IEnumerable<string> emails = GetExistingEmails();
}
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